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Pharm Basics 1
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1.pharmacology
2.pharmaceutic phase
Changing from a solid form (pill) by dissolving into a liquid form
3.pharmacokinetic
Absorption
Distribution
Metabolism
Excretion
4.Pharmacodynamic Phase
Movement of the drug into a cell & binding to cellular receptors
5.ADME Pharmacokinetic
Receptor Pharmacodynamic
Dissolve Pharmaceutic
6.Pharmacokinetics is the study of how drugs are moved throughout the body.
7. Absorption :Medication going from the location of administration to the bloodstream.
8.Distribution:Transportation of the medication by bodily fluids to where it needs to go.
Influencing Factors
:Permeability of the cell membrane
Plasma protein binding
Circulation
9.Metabolism:The break down of the medication. Most common site = LIVER.
Factors affecting metabolism: Age, First-pass effect, Medication type, Nutritional status
10.Excretion : The removal of the unmetabolized medication from the body. Primary organ = KIDNEYS.
Kidney dysfunction: Leads to an increase in the duration and intensity of a medication response.
If the kidneys aren't working to excrete waste, the medication will stay in the body which leads to toxic levels.
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